12 SUPPLEMENTS · UPDATED 2026-07-01
Prices from brand-direct stores and Amazon. Firmness, cooling, trial length, and warranty compared side-by-side. Data curated by sleep engineers — no sponsored ranking.
How to choose
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2 category winners — different needs, different picks. All editorially scored against measured specs.
11 brands compared · updated weekly
Head-to-head verdicts across 10 dimensions — active dose, form, evidence, safety, value per serving.
The mattress comparisons buyers actually search for.












Five decisions collapse this whole category into a clear pick.
For garden-variety trouble winding down, magnesium glycinate (Doctor's Best) has the better evidence-to-side-effect ratio: it supports relaxation and muscle ease without morning grogginess. Glycinate specifically — oxide (in many cheap brands) absorbs poorly and works mostly as a laxative. 200-400 mg with dinner is the studied range.
The effective dose is 0.5-1 mg taken 1-2 hours before bed — the 10 mg gummies on every shelf are marketing, and higher doses cause more grogginess without working better. Melatonin shifts TIMING (jet lag, shift work, night-owl drift); it is not a knockout pill and tolerance to that use builds fast.
Capsules (Doctor's Best, NOW) give exact dosing with no sugar. Gummies (Olly) win on compliance — you'll actually take them — at the cost of 2-3 g sugar and looser dosing. Powders let you titrate but taste like it. Pick the form you'll take consistently at the same time nightly; consistency beats format.
Magnesium interacts with some antibiotics and blood-pressure medication; melatonin with blood thinners and immunosuppressants. Pregnant, nursing, or on prescriptions → ask your pharmacist first, it's a free consult. Look for third-party testing (USP, NSF) — supplements are not FDA-approved products and the label is a promise, not a guarantee.
Doctor's Best glycinate runs about $0.17/night over a 4-month bottle — the category's best ratio. Olly gummies cost 3-4x per night for the same actives plus sugar. A $20 bottle that lasts 120 nights is the cheapest legitimate sleep intervention on this site.
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